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After sixteen-year-old Raina learns that she is a perfect match for donating bone marrow to a leukemia patient in Virginia, she discovers that the young woman is the sister she never knew she had.

With the support of her two best friends, sixteen-year-old Kathleen tries to balance her summer volunteer work at the hospital with her responsibilities caring for her mother, who has multiple sclerosis, and her attraction to a handsome boy.