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Twelve-year-old Lafayette's close relationship with his older brother Charlie changes after Charlie is released from a detention home and blames Lafayette for the death of their mother.

Kate Morrison, orphaned at the age of seven, grows up seeing her brilliant older brother Matt's failure to further his education as a tragedy, and feeling somewhat guilty about her own accomplishments, and it is not until years later that she finally sees the damage her faulty thinking has caused.

At the end of high school, Johanna finally begins dating the girl she has loved from afar, but Reeve is as much trouble as she claims to be as she and her twin brother damage Johanna's self-esteem, friendships, and already precarious relationship with her sister.

The Bailey brothers find themselves on their own after the deaths of their parents and face the challenges of raising themselves as they struggle to hold their family together on the mean streets of Harlem.

Seventeen-year-old Dani struggles with how to process the ambiguous grief she feels in the aftermath of her mother's death after moving to New Mexico with an aunt she never met.

"When the pioneering "First Family in Space" takes a catastrophic wrong turn on their maiden voyage, they crash on a dangerous alien planet.

"The other orphans say Margot is lucky. Lucky to survive the horrible accident that killed her family.

"Roy Perkins struggles in high school and has three strikes agains him.