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In 1868, with his army officer father suddenly posted to India, and his mother mysteriously "unwell," fourteen-year-old Sherlock Holmes is sent to stay with his eccentric uncle and aunt in their vast house in Hampshire, where he uncovers his first murder and a diabolical villain.

The Agency, the all-female detective unit, assigns quick-witted Mary Quinn to the case.

In 1868, teenaged Sherlock Holmes faces danger in a train station for the dead, a museum of curiousities, and downtown Moscow as he helps his brother, Mycroft, who has been framed for murder.

Sent to do volunteer work at the Whitechapel Hospital in the east end of London in 1888, seventeen-year-old Abbie discovers the identity of Jack the Ripper.

When a young boy in seventeenth-century England witnesses a lord's murder, he must find a way to reveal the killer before he becomes the next victim.

As a nearly full-fledged member of the Agency, the all-female detective unit based in Miss Scrimshaw's Academy for Girls, Mary Quinn, disguised as a poor apprentice builder, must brave the sinister underworld of Victorian London in order to unmask a murderer.

Hesitating to accept James' marriage proposal out of fear of losing her independence, Mary watches over a dying prisoner whose wife holds a grudge against James, at the same time a familiar Chinese prizefighter arrives in London.