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In 1868, with his army officer father suddenly posted to India, and his mother mysteriously "unwell," fourteen-year-old Sherlock Holmes is sent to stay with his eccentric uncle and aunt in their vast house in Hampshire, where he uncovers his first murder and a diabolical villain.

In 1868, teenaged Sherlock Holmes faces danger in a train station for the dead, a museum of curiousities, and downtown Moscow as he helps his brother, Mycroft, who has been framed for murder.