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Seventeen-year-old Lucille is struggling to get through each day, paying bills and looking after her little sister, Wren, while her father is institutionalized after a breakdown and her mother is "on vacation," but nothing else seems to matter when she is with Digby Jones, her best friend's twin brother.

After twelve-year-old Binny hides and then loses the money she found in the ATM, she asks her best frenemy Gareth to help her find the missing money so she can return it to the bank without attracting the notice of her neighbor, whom Binny believes is a witch putting spells on Binny and her family.

When thirteen-year-old Charlie compromises her values to help Lauren, one of the popular girls, cheat on a test, her identical twin sister, Sammie, is inadvertantly pulled into the mess.

From age thirteen to nineteen, Spencer experiences an ever-changing relationship with Hope, the girl next door who helps him cope with his Tourette syndrome but likes his Neanderthal brother, Dean.

"When catastrophe strikes their beloved upstairs neighbors, the Vanderbeeker children set out to build the best, most magical healing garden in Harlem--in spite of a locked fence, thistles and trash, and the conflicting plans of a wealthy real estate developer"--Provided by publisher.