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Pursued by her much older brother, famed detective Sherlock Holmes, fourteen-year-old Enola, disguised and using false names, attempts to solve the kidnapping of a baronet's sixteen-year-old daughter in nineteenth-century London.

In late nineteenth-century London, fourteen-year-old Enola Holmes, much younger sister of detective Sherlock Holmes, turns to Florence Nightingale for help when her investigation into the disappearance of a Crimean War widow grows cold.

Eighteen-year-old aspiring chemist Elinor Dashwood and her younger sister Marianne, a budding detective, work together to solve the mystery of their father's murder.

When professional typist Letitia Glover is desperate to learn more about the fate of her twin sister Flossie, Enola enlists the help of her brother Sherlock and her friend Tewky to investigate Flossie's husband, the sudden death of his first wife, and the mysterious appearance of a black barouche.