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After her overprotective grandmother has a stroke, eleven-year-old Maya, an orphan, leaves her extremely restricted life in California to stay with her mother's family on a remote Wyoming ranch, where she discovers a love of horses and encounters Artemisia, a wild mare that her mother once rode.

When twelve-year-old Elise, orphaned since age three, becomes disheartened by middle school, with its bullies, changing relationships, and higher expectations, keys to long-locked rooms and messages from her late father help her cope.

Will Tuppence's life has always been ruled by science and common sense but in ninth grade, shaken up by the discovery that protons decay, he begins to see the entire world differently and gains new perspective on his relationships with his little sister and two closest friends.

Zoe's sixth-grade year at a Brooklyn school for gifted students is marked by changing relationships with her fellow students and teachers, recognition of her talent for cryptography, and a greater awareness of her passion.

Sixteen-year-old Alex feels so disconnected from his friends that he starts his junior year at a Tuscaloosa, Alabama, high school by attempting suicide, but soon, a friend of his older brother draws him into cross-country running and a new understanding of himself.

Sky Brightman, living happily off the grid on sixty acres in New Mexico, with no television or Internet to bring her news of the war going on in the United States, is forced to face reality when her friend Kareem is unjustly arrested.

When she is abandoned by her alcoholic mother, high school senior Ruby winds up living with her sister Cora, whom she has not seen for ten years, where she learns about Cora's new life, what makes a family, how to allow people to help her when she needs it, and that she has something to offer to others as well.

Evan and Lucy, childhood best friends who grew apart after years of seeing one another only during Christmas break, begin a romance at age seventeen but his choice to mindlessly follow his father's plans for an Ivy League education rather than becoming the cartoonist he longs to be, and her more destructive choices in the wake of family problems, pull them apart.

Isolated from friends who believe the worst because she has not been truthful with them, sixteen-year-old Annabel finds an ally in classmate Owen, whose honesty and passion for music help her to face and share what really happened at the end-of-the-year party that changed her life.

JT is a gay high school senior determined to get out of Clearwater, Florida, and be the first person in his family to go to college, even though he can not figure out how to pay for it--until his friends convince him to compete in a drag teen competition where the first prize is a college scholarship.

Told in assonant free verse, Levi was once a premature baby who suffered from respiratory problems; he recovered, and now in seventh grade, he struggles to demonstrate to his divorced mother and overprotective brother that he is okay--so when his father suggests he take up boxing he falls in love with the sport, but he still must find a way to convince his family to set him free to follow his dream.

Paige Hancock starts junior year with a list of ways to take back her life, rather than spending another year as "The Girl Whose Boyfriend Drowned," and finding out that Ryan Chase, her long-term crush, is available again might be the key.

Eighteen-year-old Pakistani American Zahra makes an impulsive decision to run away from home and move to New York in an attempt to heal, learn to love herself, and renew her faith in family while navigating mental health and religious guilt.