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After meeting on the first day in Mrs. Chemsky's fifth-grade class, Margalo and Mikey help each other in and out of trouble, as they try to maintain a friendship while each asserts her independence.

Before Lewis's birthday party, Gilbert's mother wisely substitutes a toy for the frying pan Gilbert wants to give Lewis.

Grace and her group of friends, the Famous Five, face a variety of changes, including a new girl in class, taking part in the Christmas play, losing a dear friend, and challenging the grown-ups in their lives.

Herbie meets a new teacher and makes a new friend on his first day of second grade.

Best friends Raymond and Graham have looked forward to being the "oldest, coolest, toughest" boys at East Millcreek Elementary School, but from the start of fourth grade everything goes wrong, from getting the scary teacher to not getting the lead in the school play.

Catholic-schooled seventh-graders Sophie, Margaret, Rebecca, and Leigh Ann help an elderly neighbor solve a puzzle her father left for her estranged daughter twenty years ago.

It seems as if the Whatever Club is doomed when Adam insists on joining, then wants to play baseball or video games instead of reading magazines and doing other things thirteen-year-old Claudia and her girlfriends are used to doing.

When Amelia, still adjusting to life in her new neighborhood, finds out that her mother may be moving them again, she feels that her life can get no worse.

Sixth-graders Mac and Vince find their business threatened by a new administrator, hired to clean up the school, and face added dilemmas when they agree to help Trixie Von Parkway, an eighth-grader who wants to get a teacher fired and who might not be who she claims to be.

Jasper John Dooley's turn to be Star of the Week at school gets ruined when a new baby at Ori's house takes attention away from Jasper's Show and Tell, prompting him to build himself a baby brother out of wood.

The relationship between best friends Kimberly and Ann is put to the test when Ann takes a geeky new student under her wing and encourages her to compete against front runner Kimberly in the spelling bee.

Three close girlfriends, Nina, Avery, and Mel are known as the Bermudez Triangle.

Computer whiz Erin Swift starts eighth grade full of optimism, but the new school year brings a whole new set of problems, and it takes a personal tragedy to give her some perspective and help her get back on track.

Thirteen-year-old Jemma, her best friends Kate and Piper, and new student Bet are invited to join a secret society at school meant to help other girls with their problems, but membership brings many complications.

Sereeta Prince, trying to cope with problems with her family, is blamed for a string of thefts at Tubman High School and starts to fall into a depression.